About 13 results found for searched term "Liver X Receptor" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1929 | GW3965 hydrochloride | Liver X Receptor |
| GW3965 HCl | ||
| GW3965 hydrochloride is a selective, orally active non-steroidal synthetic liver X receptor (LXR) agonist. | ||
| M6087 | LXR-623 | Liver X Receptor |
| WAY-252623 | ||
| LXR-623 is a novel liver X-receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR-α and LXR-β, respectively. It is orally bioavailable and readily passes the blood-brain barrier. | ||
| M8590 | TFCA | Liver X Receptor |
| TFCA is a Liver X receptor α (LXRα) antagonist that reduces lipid accumulation and fatty liver in mice. | ||
| M8744 | IMB-808 | Liver X Receptor |
| IMB-808 is a potent Liver X receptor α and β (LXRα/β) partial dual agonist that promotes expression of genes related to reverse cholesterol transport (including ABCA1 and ABCG1), and associated with cholesterol metabolism pathway in multiple cell lines (including ApoE). | ||
| M9354 | SR9238 | Liver X Receptor |
| SR9238 is a liver X receptor (LXR) inverse agonist with IC50s of 214 nM and 43 nM for LXRα and LXRβ, respectively. | ||
| M10138 | Yamogenin | Liver X Receptor |
| Diosgenin | ||
| Yamogenin (Diosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. | ||
| M10348 | 27-Hydroxycholesterol | Estrogen Receptor |
| 27-Hydroxycholesterol is a selective estrogen receptor modulator, and it is also an agonist of the liver X receptor. | ||
| M10589 | RGX-104 | Liver X Receptor |
| SB 742881; RGX-104 free form | ||
| RGX-104, also known as SB 742881, is a liver X receptor beta (LXR) agonist with potential immunomodulating and antineoplastic activities. | ||
| M10621 | Iristectorigenin B | Liver X Receptor |
| Iristectorigenin B is a liver X receptor (LXR) modulator, which stimulates the transcriptional activity of both LXR-α and LXR-β. | ||
| M10627 | RGX-104 hydrochloride | Liver X Receptor |
| RGX104 HCl | ||
| RGX-104 hydrochloride is a small-molecule LXR (liver X receptor) agonist that modulates innate immunity via transcriptional activation of the ApoE gene. | ||
| M27669 | E1231 | Sirtuin |
| 1-{4-[2-(5-Methylfuran-2-yl)quinoline-4-carbonyl]piperazin-1-yl}ethan-1-one | ||
| E1231 is an orally active activator of Sirtuin 1 (SIRT1) (EC50=0.83 μM), to modulate cholesterol and lipid metabolism. E1231 interactes with SIRT1 (KD=9.61 μM) and deacetylated liver X receptor-alpha (LXRα), and increases ATP-binding cassette transporter A1 (ABCA1) expression. E1231 also reduces atherosclerotic plaque development in ApoE-/- mice model. E1231 can be used for research in cholesterol and lipid disorder-related diseases. | ||
| M30052 | GW3965 | Liver X Receptor |
| GW3965 is a potent, selective liver X receptor (LXR) agonist with EC50s of 190 nM and 30 nM for hLXRα and hLXRβ, respectively. | ||
| M54822 | Rovazolac | Liver X Receptor |
| ALX-101 | ||
| Rovazolac is a liver x receptor (LXR) modulator, which can be used in the study of immune system disorders and atopic dermatitis. | ||
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